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Pancreatic cancer cells elevated MARCO expression on tumor-associated macrophages and promote the development of pancreatic ductal adenocarcinoma via inhibiting adaptive immune response

2025-08-27

Abstract excerpt

<title>Abstract</title> <p> Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide. Macrophage receptor with collagenous structure (MARCO) is a scavenger receptor class-A protein expressed on the cell surface of macrophages. However, the role of MARCO-expressing macrophages in the progression of PDAC remains poorly understood. Our study revealed that MARCO-expressing macrophages signif...

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Literature Corpus work
e39e2f29-46cc-5f87-b110-38504e5768d9
DOI
10.21203/rs.3.rs-7288276/v1
Open publication

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