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Article

Tumor-associated macrophages exhibit pro- and anti-inflammatory properties by which they impact on pancreatic tumorigenesis.

International journal of cancer - 15 Aug 2014

Helm Ole, Held-Feindt Janka, Grage-Griebenow Evelin, Reiling Norbert, Ungefroren Hendrik, Vogel Ilka, Krüger Uwe, Becker Thomas, Ebsen Michael, Röcken Christoph, Kabelitz Dieter, Schäfer Heiner, Sebens Susanne

Abstract excerpt

Pancreatic ductal adenocarcinoma (PDAC) still ranking 4th in the order of fatal tumor diseases is characterized by a profound tumor stroma with high numbers of tumor-associated macrophages (TAMs). Driven by environmental factors, monocytes differentiate into M1- or M2-macrophages, the latter comm...

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Share to Antigens, Differentiation, Myelomonocytic
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24458546
DOI: 10.1002/ijc.28736

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24458546-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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