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Article

The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jul 2016

Hu Hai, Hang Jun-Jie, Han Ting, Zhuo Meng, Jiao Feng, Wang Li-Wei

Abstract excerpt

Macrophages play a critical role in the initiation and progression of various solid tumors. However, their prognostic significance in pancreatic ductal adenocarcinoma (PDAC) is poorly understood. This study investigated the distribution patterns of macrophages in PDAC and possible association with the overall survival (OS). We found significant differences in macrophage density (identified by CD68 and CD163...

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Share to Antigens, Differentiation, Myelomonocytic
Share to Carcinoma, Pancreatic Ductal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD163 Antigen

Share to Immunoenzyme Techniques

Share to Pancreatic Neoplasms

Share to Stromal Cells

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Share to Tissue Array Analysis

Source

Identifiers

PMID: 26738860
DOI: 10.1007/s13277-015-4741-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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