Article
M2-phenotype tumour-associated macrophages upregulate the expression of prognostic predictors MMP14 and INHBA in pancreatic cancer.
Journal of cellular and molecular medicine - 1 Mar 2022
Liang Zhan-Wen, Yu Jie, Gu Dong-Mei, Liu Xiao-Meng, Liu Jin, Wu Meng-Yao, Xu Meng-Dan, Shen Meng, Duan Weiming, Li Wei
Abstract excerpt
Pancreatic cancer is one of the most lethal gastrointestinal tumours, the most common pathological type is pancreatic adenocarcinoma (PAAD). In recent year, immune imbalanced in tumour microenvironment has been shown to play an important role in the evolution of tumours progression, and the efficacy of immunotherapy has been gradually demonstrated in clinical practice. In this study, we propose to construct an...
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