Article

OnionMHC: A Deep Learning Model for Peptide - HLA-A*02:01 Binding Predictions using both Structure and Sequence Feature Sets

2020-12-15

Abstract excerpt

<h4>Background: </h4> The peptide binding to Major Histocompatibility Complex (MHC) proteins is an important step in the antigen-presentation pathway. Thus, predicting the binding potential of peptides with MHC is essential for the design of peptide-based therapeutics. Most of the available machine learning-based models predict the peptide-MHC binding based on the sequence of amino acids alone. Given the importanc...

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Literature Corpus work: 57af291c-9a50-5be3-bd2a-25a8ed83f71c
DOI: 10.21203/rs.3.rs-124695/v1

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