Article

Attention mechanism-based deep learning pan-specific model for interpretable MHC-I peptide binding prediction

2019-11-04

Abstract excerpt

Accurate prediction of peptide binding affinity to the major histocompatibility complex (MHC) proteins has the potential to design better therapeutic vaccines. Previous work has shown that pan-specific prediction algorithms can achieve better prediction performance than other approaches. However, most of the top algorithms are neural networks based black box models. Here, we propose DeepAttentionPan, an improved p...

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Literature Corpus work: e157bf6d-2e26-599c-8d3f-86b9c590f82d
DOI: 10.1101/830737

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