Article

Novel kinome profiling technology reveals drug treatment is patient and 2D/3D model dependent in GBM

2022-07-23

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma is the deadliest brain cancer. One of the main reasons for poor outcome resides in therapy resistance, which adds additional challenges in finding an effective treatment. Small protein kinase inhibitors are molecules that have become widely studied for cancer treatments, including glioblastoma. However, none of these drugs have demonstrated a therapeutic activity or brought more ben...

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Literature Corpus work: e37b80b5-4696-56d3-8aac-6931f185655d
DOI: 10.1101/2022.07.22.499106

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