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Malignant glioma drug discovery – targeting protein kinases

1 Jan 2007

Abstract excerpt

Malignant gliomas are uncommon, but extremely lethal, cancers. Current standard-of-care includes surgery, radiation and chemotherapy, but recent research has generated a shift towards targeting the aberrant signal transduction components that underlie the pathogenesis of malignant gliomas. Protein kinases are a family of enzymes that are key elements in signal transduction-regulated cellular homeostasis...

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PMID: 23496034
DOI: 10.1517/17460441.2.1.1

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