Article

Development of Actionable Targets of Multi-kinase Inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells

2022-01-22

Abstract excerpt

<h4>ABSTRACT</h4> Therapeutic resistance to kinase inhibitors constitutes a major unresolved clinical challenge in cancer and especially in glioblastoma. Multi-kinase inhibitors may be used for simultaneous targeting of multiple target kinase and thereby potentially overcome kinase inhibitor resistance. However, in most cases identification of the target kinases mediating therapeutic effects of multi-kinase inhib...

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Literature Corpus work: e09df78b-f6b8-5a44-85d4-93085b02b4e2
DOI: 10.1101/2022.01.20.477108

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