Article

Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology

2021-01-18

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>Alzheimer's disease (AD) is the primary cause of cognitive deficit in elderly humans. Late-onset AD (LOAD) is sporadic, multifactorial, and non-Mendelian accounting at present for 95% of the cases in contrast to the genetic form of the disease. Risk factors for sporadic AD include Gene: Environment interactions. There is increasing evidence that lifestyle and str...

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Literature Corpus work: e3123463-786f-52b6-9ac7-8eca3c5526b6
DOI: 10.21203/rs.3.rs-145868/v1

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