Article

Systemic inflammation causes microglial dysfunction with a mixed AD-like pathology

2020-07-28

Abstract excerpt

<h4>Background</h4> Alzheimer’s disease (AD) is the primary cause of cognitive deficit in elderly humans. Late-onset AD (LOAD) is sporadic, multifactorial, non-Mendelian accounting at present for 95% of the cases in contrast to the genetic form. Risk factors for sporadic AD include Gene: Environment interactions. There is increasing evidence that lifestyle and environmental stress such as infection and chronic in...

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Literature Corpus work: 01a9c05c-e7c9-5123-b679-824e9f54877e
DOI: 10.1101/2020.07.27.223198

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