Article

Functional Connectome of Superagers Reveals Early Markers of Resilience and Vulnerability to Alzheimer’s Disease

2025-07-22

Abstract excerpt

As populations age, identifying the neurobiological basis of cognitive resilience is critical for delaying or preventing Alzheimer’s disease (AD). While most older adults experience memory decline, a subset known as superagers (SA) maintains youthful memory into late life, offering a unique window into protective mechanisms against neurodegeneration. Here, we identified a functional connectivity (FC) signature, te...

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Literature Corpus work: e311abab-abc5-51a2-b095-866d24842ece
DOI: 10.1101/2025.07.20.665707

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