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Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer’s Disease

2025-06-13

Abstract excerpt

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder defined by amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs), yet approximately 20–30% of aged individuals exhibit these hallmark lesions without developing cognitive impairment—a clinically silent condition termed asymptomatic AD (AsymAD). The molecular basis of this cognitive resilience remains poorly understood due to a lack of mech...

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Literature Corpus work
969c8e08-61a1-55f9-bca5-0ad34bd0fba1
DOI
10.1101/2025.06.11.659207
Open publication

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Boolean Network Modeling Identifies Cognitive Resilience in the First Murine Model of Asymptomatic Alzheimer’s DiseaseDOI 10.1101/2025.06.11.659207
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