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Housing laboratory mice deficient for <i>Nod2</i> and <i>Atg16l1</i> in a natural environment uncovers genetic and environmental contributions to immune variation

2019-08-21

Abstract excerpt

<h4>SUMMARY</h4> The relative contributions of genetic and environmental factors to variation in immune responses are still poorly understood. Here, we performed a deep phenotypic analysis of immunological parameters of laboratory mice released into an outdoor enclosure, carrying susceptibility genes ( Nod2 and Atg16l1 ) implicated in the development of inflammatory bowel diseases. Variations of immune cell pop...

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Literature Corpus work
e3119619-bed3-5f35-86ea-6932d396b672
DOI
10.1101/741470
Open publication

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Housing laboratory mice deficient for <i>Nod2</i> and <i>Atg16l1</i> in a natural environment uncovers genetic and environmental contributions to immune variationDOI 10.1101/741470
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