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Inflammatory bowel disease: maladaptation of the vigilant genotype in a hyper-clean world?

Perspectives in biology and medicine - 1 Jan 2006

Rajan T V

Abstract excerpt

Children born of Asian Indian parents who are raised in environmentally hygienic Western societies appear to be highly prone to two diseases, ulcerative colitis and Crohn's disease, collectively known as inflammatory bowel disease or IBD. These ethnically Indian children are similar to an inbred mouse strain, NOD/Lt. Mice of this strain remain diabetes-free when raised in standard mouse colonies, but develop an...

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PMID: 16702702
DOI: 10.1353/pbm.2006.0029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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