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Article

Type 1 diabetes susceptibility alleles are associated with distinct alterations in the gut microbiota.

Microbiome - 17 Feb 2018

Mullaney Jane A, Stephens Juliette E, Costello Mary-Ellen, Fong Cai, Geeling Brooke E, Gavin Patrick G, Wright Casey M, Spector Timothy D, Brown Matthew A, Hamilton-Williams Emma E

Abstract excerpt

BACKGROUND: Dysbiosis of the gut microbiota has been implicated in the pathogenesis of many autoimmune conditions including type 1 diabetes (T1D). It is unknown whether changes in the gut microbiota observed in T1D are due to environmental drivers, genetic risk factors, or both. Here, we have performed an analysis of associations between the gut microbiota and T1D genetic risk using the non-obese diabetic (NOD)...

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Identifiers

PMID: 29454391
DOI: 10.1186/s40168-018-0417-4
PMCID: PMC5816355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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