Article

Sex Disparities in Gastric Cancer Tumor Mutation Burden and Gene Mutation Patterns

2025-05-28

Abstract excerpt

Significant sex-related differences exist in gastric cancer, yet the molecular basis remains unclear. Tumor mutational burden (TMB) correlates with successful immune checkpoint inhibitor therapy, but TMB varies across different cancers, and evidence regarding sex-specific differences remains inconsistent. We analyzed sex-specific single-nucleotide mutations in gastric cancer using The Cancer Genome Atlas Stomach A...

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Literature Corpus work: e304b312-c2fa-5668-9188-7c5e24b4218d
DOI: 10.1101/2025.05.24.655976

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