Article
The association of sex-biased ATRX mutation in female gastric cancer patients with enhanced immunotherapy-related anticancer immunity.
BMC cancer - 7 Mar 2021
Ge You, Wei Feiran, Du Guoping, Fei Gaoqiang, Li Wei, Li Xiaoshan, Chu Jinjin, Wei Pingmin
Abstract excerpt
BACKGROUND: Genetic alterations have been proven to be the promising biomarkers for ICI response. However, sex biases in genetic alterations have been often ignored in the field of immunotherapy, which might specially influence the anticancer immunity and immunotherapy efficacy in male or female patients. Here, we have systematically evaluated the effect of the sex biases in somatic mutation of gastric cancer...
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