Article
Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients.
Cancer cell - 9 May 2016
Yuan Yuan, Liu Lingxiang, Chen Hu, Wang Yumeng, Xu Yanxun, Mao Huzhang, Li Jun, Mills Gordon B, Shu Yongqian, Li Liang, Liang Han
Abstract excerpt
An individual's sex has been long recognized as a key factor affecting cancer incidence, prognosis, and treatment responses. However, the molecular basis for sex disparities in cancer remains poorly understood. We performed a comprehensive analysis of molecular differences between male and female patients in 13 cancer types of The Cancer Genome Atlas and revealed two sex-effect groups associated with distinct...
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