Article

Effect of Nutrient Metabolism on Cartilaginous Tissue Formation

2021-01-23

Abstract excerpt

Despite the potential of tissue engineering approaches for cartilage repair, a major shortcoming is the low biosynthetic response of chondrocytes. While different strategies have been investigated to upregulate tissue formation, a novel approach may be to control nutrient metabolism. Although known for their anaerobic metabolism of glucose, chondrocytes are more synthetically active when cultured under conditions...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e2fd8dbf-b74a-58e7-88aa-30411bf43b23
DOI: 10.22541/au.161140633.32132152/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Effect of Nutrient Metabolism on Cartilaginous Tissue FormationDOI 10.22541/au.161140633.32132152/v1Read

13C Metabolic Flux Analysis in Chondrocytes Reveals a Novel Switch in Metabolic Phenotype.Semantic proximity Read

Toward Standardized Ex Vivo Joint Models: Impact of Glucose and Oxygen Levels for Enhanced Tissue MaintenanceSemantic proximity Read

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identifiedSemantic proximity Read

2P-FLIM unveils time-dependent metabolic shifts during osteogenic differentiation with a key role of lactate to fuel osteogenesis via glutaminolysis identifiedSemantic proximity Read

Metabolomic Profiling and Characterization of a Novel 3D Culture System for Studying Chondrocyte MechanotransductionSemantic proximity Read

Metabolic reprogramming in chondrocytes to promote mitochondrial respiration reduces downstream features of osteoarthritisSemantic proximity Read

Physiological Dynamic Compression Regulates Central Energy Metabolism in Primary Human ChondrocytesSemantic proximity Read

Metabolic utilization of human osteoblast cell line hFOB 1.19 under normoxic and hypoxic conditions: A phenotypic microarray analysis.Semantic proximity Read

Modeling the role of ATP metabolism in articular cartilage and osteoarthritisSemantic proximity Read

Metabolic Reprogramming of Fibroblasts as Therapeutic Target in Rheumatoid Arthritis and Cancer: Deciphering Key Mechanisms using Computational Systems Biology ApproachesSemantic proximity Read

MYC overrides HIF to regulate proliferating primary cell metabolism in hypoxiaSemantic proximity Read

Lactate Metabolism in the Intervertebral Disc: Mechanistic Insights and Pathological ImplicationsSemantic proximity Read