Article
Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning
15 Feb 2018
Abstract excerpt
The nephron is the functional unit of the kidney, but the mechanism of nephron formation during human development is unclear. We conducted a detailed analysis of nephron development in humans and mice by immunolabeling, and we compared human and mouse nephron patterning to describe conserved and divergent features. We created protein localization maps that highlight the emerging patterns along the proximal–distal...
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