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The Cellular Basis of Kidney Development

5 Jul 2006

Abstract excerpt

Mammalian kidney development has helped elucidate the general concepts of mesenchymal-epithelial interactions, inductive signaling, epithelial cell polarization, and branching morphogenesis. Through the use of genetically engineered mouse models, the manipulation of Xenopus and chick embryos, and the identification of human renal disease genes, the molecular bases for many of the early events in the developing...

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PMID: 16822174
DOI: 10.1146/annurev.cellbio.22.010305.104340

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