Article

<i>osr1</i> maintains renal progenitors and regulates podocyte development by promoting <i>wnt2ba</i> through antagonism of <i>hand2</i>

2020-12-22

Abstract excerpt

<h4>ABSTRACT</h4> Knowledge about the genetic pathways that control renal cell lineage development is essential to better understand the basis of congenital malformations of the kidney and design regenerative medicine therapies. The embryonic zebrafish kidney, or pronephros, contains two nephrons that are conserved with humans. Recently, the transcription factors Osr1 and Hand2 were found to exert antagonistic in...

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Literature Corpus work: 76366be4-7036-563b-a6b0-078c95ba4e7c
DOI: 10.1101/2020.12.21.423845

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