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A coordinated progression of progenitor cell states initiates urinary tract development

11 May 2021

Abstract excerpt

The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud and the surrounding mesenchyme. Ureteric bud branching forms the arborized collecting duct system of the kidney, while ureteric tips promote nephron formation from dedicated progenitor cells. While nephron progenitor cells are relatively well characterized, the origin of ureteric bud progenitors has received little...

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PMID: 33976190
DOI: 10.1038/s41467-021-22931-5

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