Article

Sexual dimorphism in epigenomic responses of stem cells to extreme fetal growth

2014-08-27

Abstract excerpt

<h4>ABSTRACT</h4> Extreme fetal growth is associated with increased susceptibility to a range of adult diseases through an unknown mechanism of cellular memory. We tested whether heritable epigenetic processes in long-lived CD34+ hematopoietic stem/progenitor cells (HSPCs) showed evidence for re-programming associated with the extremes of fetal growth. Here we show that both fetal growth restriction and over-grow...

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Literature Corpus work: e2f3670b-f5c1-5f39-909e-666d95b7dce1
DOI: 10.1101/008482

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