Article
Birth Weight Is Associated With Clonal Hematopoiesis of Indeterminate Potential and Cardiovascular Outcomes in Adulthood.
Journal of the American Heart Association - 4 Jul 2023
Schuermans Art, Nakao Tetsushi, Ruan Yunfeng, Koyama Satoshi, Yu Zhi, Uddin Md Mesbah, Haidermota Sara, Hornsby Whitney, Lewandowski Adam J, Bick Alexander G, Niroula Abhishek, Jaiswal Siddhartha, Ebert Benjamin L, Natarajan Pradeep, Honigberg Michael C
Abstract excerpt
Background High and low birth weight are independently associated with increased cardiovascular disease risk in adulthood. Clonal hematopoiesis of indeterminate potential (CHIP), the age-related clonal expansion of hematopoietic cells with preleukemic somatic mutations, predicts incident cardiovascular disease independent of traditional cardiovascular risk factors. Whether birth weight predicts development of...
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