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Article

Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates

11 Dec 2014

Abstract excerpt

Fetal growth is determined by the feto-placental genome interacting with the maternal in utero environment. Failure of this interplay leads to poor placental development and fetal growth restriction (FGR), which is associated with future metabolic disease. We investigated whether whole genome methylation differences existed in umbilical cord blood and placenta, between gestational-matched, FGR, and appropriately...

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Share to Birth, Development, and Health
Share to Epigenetics and DNA Methylation
Share to Pregnancy and preeclampsia studies

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PMID: 25496377
DOI: 10.4161/15592294.2014.989741

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