Article

Increased atherosclerosis and expression of inflammarafts in macrophage foam cells in AIBP-deficient mice

2025-08-15

Abstract excerpt

Atherosclerotic lesions comprise different populations of macrophages, including lipid-laden macrophage foam cells and non-foamy, inflammatory macrophages, which play distinct roles in disease progression. Non-foamy macrophages express higher levels of inflammarafts – enlarged, cholesterol-rich lipid rafts hosting assemblies of inflammatory receptors – compared to foam cells in atherosclerotic lesions of Ldlr −/...

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Literature Corpus work: e2e4a4ee-ac8c-535f-aa83-07a2fad83144
DOI: 10.1101/2025.08.12.669996

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