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Article

Foam cell formation: A new target for fighting atherosclerosis and cardiovascular disease.

Vascular pharmacology - 1 Jan 2019

Maguire Eithne M, Pearce Stuart W A, Xiao Qingzhong

Abstract excerpt

During atherosclerosis, the gradual accumulation of lipids into the subendothelial space of damaged arteries results in several lipid modification processes followed by macrophage uptake in the arterial wall. The way in which these modified lipoproteins are dealt with determines the likelihood of cholesterol accumulation within the monocyte-derived macrophage and thus its transformation into the foam cell that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30115528
DOI: 10.1016/j.vph.2018.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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