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Article

Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease.

Neurobiology of disease - 1 Feb 2015

Glaab Enrico, Schneider Reinhard

Abstract excerpt

Aging is considered as one of the main factors promoting the risk for Parkinson's disease (PD), and common mechanisms of dopamine neuron degeneration in aging and PD have been proposed in recent years. Here, we use a statistical meta-analysis of human brain transcriptomics data to investigate potential mechanistic relationships between adult brain aging and PD pathogenesis at the pathway and network level. The...

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PMID: 25447234
DOI: 10.1016/j.nbd.2014.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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