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Article

Multi-omics analysis reveals the genetic aging landscape of Parkinson's disease.

Scientific reports - 28 Dec 2024

Wang Zihao, Zhang Zhan, Li Peishan, Cao Qiannan, Fan Peidong, Xia Huan, Yang Xinling

Abstract excerpt

Parkinson's disease (PD) is the second most common age-related neurodegenerative disease after Alzheimer's disease. Despite numerous studies, specific age-related factors remain unidentified. This study employed a multi-omics approach to investigate the link between PD and aging. We integrated blood gene expression profiles, expression quantitative trait loci, genome-wide association studies, predictive models,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39730760
DOI: 10.1038/s41598-024-82470-z
PMCID: PMC11680984

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