Article

Mechano-modulatory synthetic niches for liver organoid derivation

2019-10-18

Abstract excerpt

The recent demonstration that primary cells from the liver can be expanded in vitro as organoids holds enormous promise for regenerative medicine and disease modeling 1–5 . The use of three-dimensional (3D) cultures based on ill-defined and potentially immunogenic matrices, however, hampers the translation of liver organoid technology into real-life applications 6 . We here used chemically defined hydrogels for...

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Literature Corpus work: e2b192d9-b734-52f6-beb3-ba289a07b8eb
DOI: 10.1101/810275

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