Article

MET functions in tumour progression and therapy resistance are repressed by intronic polyadenylation

2023-08-09

Abstract excerpt

Intronic polyadenylation (IPA) leads to the production of transcript isoforms with alternative last exons in thousands of mammalian genes. Widespread regulation of IPA isoforms was observed during oncogenic transformation and in tumours versus healthy tissues, and several IPA isoforms were involved in oncogenesis. However, little is known about the potential involvement of IPA in tumour progression, such as cance...

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Literature Corpus work: e2ae3add-db3e-5d44-951d-c62cc50f4abc
DOI: 10.1101/2023.08.09.552237

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