Article

Quality of Whole Genome Sequencing from Blood versus Saliva Derived DNA in Cardiac Patients

2019-01-28

Abstract excerpt

Whole-genome sequencing (WGS) is becoming an increasingly important tool for detecting genomic variation. Blood derived DNA is the current standard for WGS for research or clinical purposes. We compared the level of microbial contamination, sequencing coverage, as well as yield and concordance of single-nucleotide polymorphism (SNP) and copy number variant (CNV) calls in WGS from paired blood and saliva samples fr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e2a72365-9d61-5464-b598-e3cac712e480
DOI: 10.1101/532564

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quality of Whole Genome Sequencing from Blood versus Saliva Derived DNA in Cardiac PatientsDOI 10.1101/532564Read

Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patientsSemantic proximity Read

Contaminating DNA in human saliva alters the detection of variants from whole genome sequencing.Semantic proximity Read

Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing data.Semantic proximity Read

Chromosomal Microarray Detection of Constitutional Copy Number Variation Using Saliva DNA.Semantic proximity Read

DNA from dried blood spots yields high quality sequences for exome analysisSemantic proximity Read

Collection and Extraction of Saliva DNA for Next Generation SequencingSemantic proximity Read

Validation of whole genome sequencing from dried blood spots.Semantic proximity Read

Array-based whole-genome survey of dog saliva DNA yields high quality SNP data.Semantic proximity Read

Reliability of high-throughput genotyping of whole genome amplified DNA in SNP genotyping studies.Semantic proximity Read

Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing dataSemantic proximity Read

DNA quantification of whole genome amplified samples for genotyping on a multiplexed bead array platform.Semantic proximity Read

Saliva-derived DNA performs well in large-scale, high-density single-nucleotide polymorphism microarray studies.Semantic proximity Read