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Article

Chromosomal Microarray Detection of Constitutional Copy Number Variation Using Saliva DNA.

The Journal of molecular diagnostics : JMD - 1 May 2017

Reiner Jennifer, Karger Lisa, Cohen Ninette, Mehta Lakshmi, Edelmann Lisa, Scott Stuart A

Abstract excerpt

Chromosomal microarray (CMA) testing to detect copy number aberrations among individuals with multiple congenital anomalies and/or developmental delay is typically performed on peripheral blood DNA. However, the use of saliva DNA may be preferred for some patients, which prompted our validation study using six saliva DNA samples with a range of bacterial content (approximately 3% to 21%) and 20 paired blood and...

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Share to Chromosome Aberrations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28315673
DOI: 10.1016/j.jmoldx.2016.11.006
PMCID: PMC5417105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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