Article

Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing data

2020-11-16

Abstract excerpt

This study sets out to establish the suitability of saliva-based whole-genome sequencing (WGS) through a comparison against blood-based WGS. To fully appraise the observed differences, we developed a novel technique of pseudo-replicates. We also investigated the potential of characterising individual salivary microbiomes from non-human DNA fragments found in saliva. We observed the majority of discordant genotype...

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Literature Corpus work: a98bd486-4905-5619-a1ab-78a8ec06a488
DOI: 10.1101/2020.11.16.384438

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