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Quality of whole genome sequencing from blood versus saliva derived DNA in cardiac patients

29 Jan 2020

Abstract excerpt

BACKGROUND: Whole-genome sequencing (WGS) is becoming an increasingly important tool for detecting genomic variation. Blood derived DNA is the current standard for WGS for research or clinical purposes but may not always be feasible to acquire. The usability of DNA from saliva for WGS is not known. We compared the quality of WGS between blood versus saliva derived DNA. METHODS: WGS was performed in DNA from 531...

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PMID: 31996208
DOI: 10.1186/s12920-020-0664-7

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