Article
Navigating the immunometabolic heterogeneity of B cells in murine hepatocellular carcinoma at single cell resolution.
International immunopharmacology - 1 Jul 2023
Zhao Xindong, Zhang Huanran, Han Yiru, Fang Chengyu, Liu Jingqi
Abstract excerpt
Induction of antitumor immunity is critical for the therapeutic efficacy of hepatocellular carcinoma (HCC) immunotherapy. The cellular metabolic state underpins the effector function of immune cells, yet our understanding of the phenotypic and metabolic heterogeneity of B cells within HCC microenvironment is poorly developed. Herein, we investigated the composition, distribution, phenotype, function and metabolic...
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