Article

Variant antigen diversity in <i>Trypanosoma vivax</i> is not driven by recombination

2019-08-20

Abstract excerpt

African trypanosomes are vector-borne haemoparasites that cause African trypanosomiasis in humans and animals. Parasite survival in the bloodstream depends on immune evasion, achieved by antigenic variation of the Variant Surface Glycoprotein (VSG) coating the trypanosome cell surface. Recombination, or rather directed gene conversion, is fundamental in Trypanosoma brucei , as both a mechanism of VSG gene switch...

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Literature Corpus work: e252963a-7893-57c9-923c-077d0df6689c
DOI: 10.1101/733998

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