Article

Variant surface glycoprotein diversity in African trypanosomes

2018-01-01

Abstract excerpt

African trypanosomes are vector-borne haemoparasites that cause animal and human African trypanosomiasis. Survival in the mammal host is mediated by antigenic variation, an immune evasion mechanism based on the sequential replacement of the Variant Surface Glycoprotein (VSG) coat that covers the parasite surface. As the main factors in the host-trypanosome interaction, VSG expression and structure has been extensi...

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Literature Corpus work: fe9095f3-416a-5b4d-8cf3-818692889f44
DOI: 10.17638/03021401

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