Article

Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast

2021-02-08

Abstract excerpt

<title>Abstract</title> <p>There is an unmet clinical need for stratification of breast lesions as indolent or aggressive to tailor treatment. Here, single-cell transcriptomics and multiparametric imaging applied to a mouse model of breast cancer revealed that the aggressive tumor niche is characterized by an expanded basal-like population, specialization of tumor subpopulations, and mixed-lineage tumor cells pot...

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Literature Corpus work: 7084ea13-9fb1-58ac-8463-d99318b6c42a
DOI: 10.21203/rs.3.rs-179498/v1

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