Article
Molecular and cellular phenotypic differences distinguish murine syngeneic models from human tumors
2019-07-05
Abstract excerpt
<h4> Abstract </h4> The clinical success of immune checkpoint inhibitors that target cytotoxic T-lymphocyte associated protein 4 (CTLA4) and programmed cell death protein 1 (PD-1) or programmed death ligand-1 (PD-L1) demonstrates that reactivation of the human immune system delivers durable responses for some patients and represents an exciting approach for cancer treatment. The combination of multiple immunothe...
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Identifiers and source
- Literature Corpus work
- d9fb1888-fb3a-55c5-814d-0b6831ee5f1b
- DOI
- 10.1101/694232