Article

Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus Inoculation

2024-10-03

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Respiratory viral infections produce highly variable clinical outcomes, even after controlled exposure. Human viral challenge studies are well suited to study this variation because they capture immune profiles before inoculation and across defined post-challenge intervals. However, how circulating immune-cell populations change over time, and which responses are shared or v...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e245c46b-ccbb-55c4-bb77-8956d119b793
DOI: 10.1101/2024.10.01.616122

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Temporal High-Resolution Atlas of Human Blood Leukocyte Composition in Response to Respiratory Virus InoculationDOI 10.1101/2024.10.01.616122Read

A curated collection of transcriptome datasets to study the transcriptional response in blood and nasal samples following viral respiratory inoculation and vaccinationSemantic proximity Read

Human SARS-CoV-2 challenge uncovers local and systemic response dynamicsSemantic proximity Read

Human SARS-CoV-2 challenge resolves local and systemic response dynamicsSemantic proximity Read

Analysis of respiratory and systemic immune responses in COVID-19 reveals mechanisms of disease pathogenesisSemantic proximity Read

<i>home</i>RNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studySemantic proximity Read

Integrated single-cell analysis reveals interferon-driven immune signatures in a DENV1 human infection modelSemantic proximity Read

People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burdenSemantic proximity Read

SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infectionsSemantic proximity Read

SARS-CoV-2 human challenge reveals single-gene blood transcriptional biomarkers that discriminate early and late phases of acute respiratory viral infectionsSemantic proximity Read

Landscape of coordinated immune responses to H1N1 challenge in humansSemantic proximity Read

Sustained IFN signaling is associated with delayed development of SARS-CoV-2-specific immunitySemantic proximity Read

Multi-omic Profiling Reveals Early Immunological Indicators for Identifying COVID-19 ProgressorsSemantic proximity Read