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Article

Landscape of coordinated immune responses to H1N1 challenge in humans

11 Oct 2020

Abstract excerpt

Influenza is a significant cause of morbidity and mortality worldwide. Here we show changes in the abundance and activation states of more than 50 immune cell subsets in 35 individuals over 11 time points during human A/California/2009 (H1N1) virus challenge monitored using mass cytometry along with other clinical assessments. Peak change in monocyte, B cell, and T cell subset frequencies coincided with peak...

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PMID: 33044226
DOI: 10.1172/jci137265

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