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SARS-CoV-2 human challenge reveals biomarkers that discriminate early and late phases of respiratory viral infections

30 Nov 2024

Abstract excerpt

Blood transcriptional biomarkers of acute viral infections typically reflect type 1 interferon (IFN) signalling, but it is not known whether there are biological differences in their regulation that can be leveraged for distinct translational applications. We use high frequency sampling in the SARS-CoV-2 human challenge model to show induction of IFN-stimulated gene (ISG) expression with different temporal and...

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PMID: 39616162
DOI: 10.1038/s41467-024-54764-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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