Article

CD4 <sup>+</sup> Foxp3E2 <sup>+</sup> regulatory T cell frequency predicts breast cancer prognosis and recurrence

2024-09-07

Abstract excerpt

CD4 + Foxp3 + regulatory T cells (Tregs) are key to maintain peripheral self -tolerance and suppress immune responses to tumors. Their accumulation in the tumor microenvironment (TME) correlates with poor clinical outcome in several human cancers, including breast cancer (BC). However, the properties of intratumoral Tregs remain largely unknown. Here, we found that a functionally distinct subpopulation of tumor...

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Literature Corpus work: e217ff8c-d523-50f8-bd49-15ab669ca048
DOI: 10.1101/2024.09.04.611142

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CD4 <sup>+</sup> Foxp3E2 <sup>+</sup> regulatory T cell frequency predicts breast cancer prognosis and recurrenceDOI 10.1101/2024.09.04.611142Read

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