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Article

Bioinformatic Analysis of Immune Significance of RYR2 Mutation in Breast Cancer.

BioMed research international - 1 Jan 2021

Xu Zhiquan, Xiang Ling, Wang Rong, Xiong Yongfu, Zhou He, Gu Haitao, Wang Jijian, Peng Linglong

Abstract excerpt

BACKGROUND: Currently, immunotherapy is widely used for breast cancer (BC) patients, and tumor mutation burden (TMB) is regarded as a valuable independent predictor of response to immunotherapy. However, specific gene mutations and their relationship with TMB and tumor-infiltrating immune cells in BC are not fully understood. METHODS: Comprehensive bioinformatic analyses were performed using data from The Cancer...

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Identifiers

PMID: 34888385
DOI: 10.1155/2021/8072796
PMCID: PMC8651385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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