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Article

Preferential accumulation of regulatory T cells with highly immunosuppressive characteristics in breast tumor microenvironment.

Oncotarget - 16 May 2017

Syed Khaja Azharuddin Sajid, Toor Salman M, El Salhat Haytham, Faour Issam, Ul Haq Navid, Ali Bassam R, Elkord Eyad

Abstract excerpt

Immunosuppressive cells such as regulatory T cells (Tregs) have an ambiguous role in breast cancer prognosis, with studies reporting both positive and negative correlations between Treg infiltration and prognosis. This discrepancy could be due to the different immunosuppressive molecules present in these cells. In the present study, we phenotypically characterize different Treg subsets infiltrating the tumor...

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Identifiers

PMID: 28388539
DOI: 10.18632/oncotarget.16565
PMCID: PMC5464858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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