Article

MATE-Seq: Microfluidic Antigen-TCR Engagement Sequencing

2019-07-18

Abstract excerpt

Adaptive immunity is based on peptide antigen recognition. Our ability to harness the immune system for therapeutic gain relies on the discovery of the T cell receptor (TCR) genes that selectively target antigens from infections, mutated proteins, and foreign agents. Here we present a method that selectively labels peptide antigen-specific CD8+ T-cells in human blood using magnetic nanoparticles functionalized wit...

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Literature Corpus work: e211ac0c-8cc7-523a-b8c3-a401516a27ca
DOI: 10.1101/706606

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