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A universal MHCII technology platform to characterize antigen-specific CD4+ T cells

1 Jan 2023

Abstract excerpt

CD4+ T cells are critical to the immune system and perform multiple functions; therefore, their identification and characterization are crucial to better understanding the immune system in both health and disease states. However, current methods rarely preserve their ex vivo phenotype, thus limiting our understanding of their in vivo functions. Here we introduce a flexible, rapid, and robust platform for ex vivo...

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PMID: 36814840
DOI: 10.1016/j.crmeth.2022.100388

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